Treatment of Acute Uncomplicated Cystitis. A Clinical Review

The incidence of cystitis is much higher than that of pyelonephritis. Uncomplicated UTIs are episodios of acute cystitis or pyelonephritis when it occurs in a healthy premenopausal, non-pregnant woman with no known urological abnormalities (structural or functional) [1-5]. UTI that do not meet these criteria is considered complicated. This review is focused on management of acute uncomplciated cystitis. Although some experts may consider “uncomplicated” those UTIs occurring in postmenopausal women or in well-controlled diabetic women without urological sequelae [6] a discussion of specific management of these groups is beyond the scope of this article. In 2011, the Infectious Diseases Society of America (IDSA) in collaboration with the European Society for Microbiology and Infectious Diseases (ESCMID) published a clinical practice guideline on the treatment of women with acute uncomplicated cystitis and pyelonephritis [1].